Publications

RUNX1 loss renders hematopoietic and leukemic cells dependent on interleukin-3 and sensitive to JAK inhibition
Journal of Clinical Investigation
Fan, A.C., Nakauchi, Y., Bai, L., Azizi, A., Nuno, K.A., Zhao, F., Karigane, D., Cruz-Hernandez, D., Reinisch, A., Khatri, P., Majeti, R.
2023;e167053

Reprogramming Cancer into Antigen Presenting Cells as a Novel Immunotherapy
Cancer Discovery
Linde, M.H., Fan, A.C., Köhnke, T., Trotman-Grant, A.C., Gurev, S.F., Phan, P., Zhao, F., Haddock, N.L., Nuno, K.A., Gars, E.J., Stafford, M., Marshall, P.L., Dove, C.G., Linde, I.L., Landberg, N., Miller, L.P., Majzner, R.G., Zhang, T.Y., Majeti, R.
2023;13(5):1164-1185

The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia
Blood Cancer Discovery
Nakauchi, Y., Azizi, A., Thomas, D., Corces, M., Reinisch, A., Sharma, R., Cruz Hernandez D., Köhnke, T., Karigane, D., Fan, A., Martinez-Krams, D., Stafford, M., Kaur, S., Dutta, R., Phan, P., McCarthy, E., Ning, Y., Phillips, T., Ellison, C., Guler, G., Bergamaschi, A., Ku, C-J., Levy, S., Majeti, R.
2022;3(4):346-367.

Black In Immuno: using social media and digital platforms to connect the dots
Nature Reviews Immunology
Babdor, J., Fan, A.C., Wane, M., Mbiribindi, B., Mobley, A.S., Noel, J.C., Kouame, E.
2021; 21: 756-757.

Black In Immuno Week: Who We Are, What We Did, and Why It Matters
Journal of Immunology
Kouame, E., Noel, J.C., Wane, M., Babdor, J., Caslin, H.L., Fan, A., Mbiribindi, B., Sattler, S., Mobley, A.S.
2021; 207(8): 1941-1947.

NOT-Gated CD93 CAR T Cells Effectively Target AML with Minimized Endothelial Cross-Reactivity.
Blood Cancer Discovery
Richards, R., Zhao, F., Freitas, K., Parker, K., Xu, P., Fan, A., Sotillo, E., Daugaard, M., Oo, H.Z., Liu, J., Hong, W-J., Sorenson, P., Chang, H., Satpathy, A., Majzner, R., Majeti, R., Mackall, C.
2021; 2(6): 648-665.

Niche-Directed Therapy in Acute Myeloid Leukemia: Optimization of Stem Cell Competition for Niche Occupancy
Leukemia & Lymphoma
Patel, S.A., Dalela, D, Fan, A.C., Lloyd, M.R., Zhang, T.
2021; 63(1): 10-18.

Hybridization-based capture of pathogen mRNA enables paired host-pathogen transcriptional analysis
Science Reports
Betin, V.,* Penaranda, C.,* Bandyopadhyay, N., Yang, R., Abitua, A., Bhattacharyya, R., Fan, A., Avraham, R., Livny, J., Shoresh, N., Hung, DT.
2018; 9: 19244.

scDual-Seq: mapping the gene regulatory program of Salmonella infection by host and pathogen single-cell RNA-sequencing
Genome biology
Avital, G.,* Avraham, R.,* Fan, A., Hashimshony, T., Hung, D. T., Yanai, I.
2017; 18: 200

A highly multiplexed and sensitive RNA-seq protocol for simultaneous analysis of host and pathogen transcriptomes.
Nature protocols
Avraham, R., Haseley, N., Fan, A., Bloom-Ackermann, Z., Livny, J., Hung, D. T.
2016; 11 (8): 1477-1491

Selected Presentations

Interleukin-3 selectively rescues RUNX1-deficient human HSPCs with hyposensitivity to JAK/STAT signaling.
Selected Oral.
International Society of Experimental Hematology Annual Scientific Meeting, 2022.

Hypersensitivity to IL-3 Rescues Inflammatory RUNX1-Deficient Human HSPCs.
Selected Oral & Poster.
International Society of Experimental Hematology Annual Scientific Meeting, 2021.
International Society of Experimental Hematology Travel Grant

Cytokine Rescue and Targeting of Inflammation-Sensitive RUNX1 Deficient Human CD34+ Hematopoietic Stem and Progenitor Cells
Selected Oral.
American Society of Hematology Annual Meeting and Exhibition, 2020.
ASH Abstract Achievement Award.

Cytokine Rescue of Inflammation-Sensitive RUNX1 Deficient Human CD34+ Hematopoietic Stem and Progenitor Cells
Selected Oral.
Stanford Immunology Annual Scientific Conference, 2020.
Best Graduate Student Talk.

IL-3 rescues proliferative defects in inflammation-sensitive RUNX1 deficient human hematopoietic stem and progenitor cells
Selected Poster.
International Society of Experimental Hematology Annual Scientific Meeting, 2020.

Modeling the pathogenesis of RUNX1 deficiency in inherited AML predisposition syndromes in primary cells.
Selected Poster.
International Society of Experimental Hematology Annual Scientific Meeting, 2019.
Stanford Biosciences Travel Grant

Cell Autonomous and Non-Autonomous Effects of RUNX1 Deficiency in Inherited AML Predisposition Syndromes
Selected Poster.
International Society of Experimental Hematology Annual Scientific Meeting, 2018.
Stanford Biosciences Travel Grant

Single-cell RNA-Seq for simultaneous transcriptome analysis of host and pathogen
Selected Poster.
Microbial Pathogenesis & Host Response: Cold Spring Harbor Laboratory, 2015.